
Conifer Point pairs AI with fragment-based design to accelerate preclinical discovery. Bring us a target. We'll show you the chemistry that binds it.

















Conifer Point is a contract research organization specializing in preclinical drug discovery. We give academic, nonprofit, and industrial teams access to cutting-edge modeling — no software, hardware, or comp-chem hire required.
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Hover or select a stage to see the computational services and tools Conifer Point brings to it.
From traditional small molecules to designed proteins and applications beyond human therapeutics — our methods generalize across challenging targets.
Our web application for AI-assisted and fragment-based drug design. Drag and drop your compounds, choose from a 500+ protein library with pre-computed water and fragment maps — or upload your own structures — and answer the questions that matter: where does it bind, and what makes it bind better?
Halos colored by binding strength; quantitative water and hot-spot reporting.
π–π and H-bond highlights with QM energies and ligand ΔΔG scoring.
Turn plain-language goals into automated workflows with scientific summaries.
Predict structures with Boltz-1/2 and Chai-1 right in your browser.
Bryan et al.
Sato, … Kulp et al.
Kulp et al.
Tell us about your program and we'll show you where the fragments bind. A computational chemist follows up within two business days.